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                                      Rabbit    Anti-AQP2 

Catalog Number :    HZ323213                    Quantity size :      0.1ml    （dilute with pH 

7.4        0.01 M PBS or antibody diluent ）   

Background:        Aquaporins （AQPs） are a large family of integral  membrane water 

transport channel proteins that facilitate the transport of water through the cell mem- 

brane. This function is conserved in animals, plants and bacteria. Many isoforms of 

aquaporin  have  been  identified  in  mammals,  designated  AQP0  through  AQP10. 

Aquaporins are widely distributed and it is not uncommon for more than one type of 

AQP to be present in the same cell. Although most aquaporins are only permeable to 

water, AQP3, AQP7, AQP9 and one of the two AQP10 transcripts are also permeable 

to urea and glycerol. AQP2 is the only water channel that is activated by vasopressin 

to enhance water reabsorption in the kidney collecting duct. Aquaporins are involved 

in  renal  water  absorption,  generation  of  pulmonary  secretions,  lacrimation  and  the 

secretion and reabsorption of cerebrospinal fluid and aqueous humor. AQP1 is an 

integral membrane protein expressed in erythrocytes and renal tubule cells. 

pecificity :         

 –    Anti-AQP2 is a rabbit polyclonal antibody unconjugated                                   

 –    specific for AQP2 of human, mouse, rat                       

 –     use for western blotting,elisa,immunoprecipitation and immunohistochemistry 

 –     Protein A affinity chromatography purification, purity :>95% 

 –     Isotype:    IgG 

 –     mol wt:    29kDa   

 Application :       

 –    Western blotting 1:100-500                                   

 –     Immunohistochemistry 1:100-500                                     

 –     ELISA 1:500-1000                                       

 –     Optimal working dilutions must    be determined by the end user. 

  Storage:    Store  at  -20℃  for  one  year.  Avoid  repeated  freeze/thaw  cycles.  The   

  lyophilized  antibody  is  stable  at  room  temperature  for  at  least  one  month  and  for 

  greater    than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M 

  PBS or diluent    of antibody, the antibody is stable for at least six weeks at 2-4  ℃ 

   Important Note: This product as supplied is intended for research use only, not for 

  use in    human, therapeutic or diagnostic applications.